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EPA (eicosapentanoic acid)
 
There are very few sources of EPA in the diet. It can be made from the omega-3 oil alpha-linolenic acid found in large amounts in flax oil, in moderate amounts in canola oil and walnuts or in small amounts in green leafy vegetables. This process is hindered in various disease states and requires that some people get EPA from their diet or supplementally. The average American's diet, however, is now low in EPA, resulting from a declining consumption of dietary sources of EPA such as fatty fish and animal organ meats.

Vegetarians have lower blood levels of EPA due to its absence in foods of plant origin. Fish obtain their DHA and EPA ultimately from the consumption of algae. Some conditions are treated predominantly with EPA and others with DHA. Since EPA and DHA seem to compete with each other, taking a blend of the two has proven not to produce the expected benefits in some conditions. The change is slow and requires about 10 months of supplementation. However, the result of the study suggests that supplementation with ALA from flax oil may to some degree have the same beneficial role as supplementation with fish oil.

This news may be particularly interesting to people following a vegetarian diet or for those who do not eat fish products. [Journal of Nutrition Science Viturminol, December 1999]. Sources with a high EPA/DHA ratio are prepared from fish oils. There is currently no product available which contains EPA without any DHA. Supplemental sources with high DHA/EPA ratios are now available that have been derived from algae. Eggs are now available which contain EPA and DHA when the chickens have been fed special diets containing these fatty acids or flax seed. Therapeutic EPA doses are in the range of 500 to 2,500mg per day, depending on the condition being treated.
 
EPA (eicosapentanoic acid) benefits or hinders:
 
Bipolar Disorder, Manic-Depressive
Depression