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| Glycyrrhizin is one of the active constituents of licorice. It possesses antidepressant effects, and heals mucous membranes of the digestive tract. Most of us know of the sweet taste of licorice (Glycyrrhiza glabra) root. Used for many years to flavor the candy of the same name, licorice has since been replaced by anise and other flavorings in this popular treat. Chewable tablets and other licorice products for extended anti-ulcer therapy now often contain very little (just 2% or less) of the active component glycyrrhizin (also known as glycyrrhizic acid). These deglycyrrhizinated licorice (DGL) products cause fewer side-effects and are much safer for long-term use than glycyrrhizin-containing licorice. An average dose of DGL licorice is 200mg. They apparently work by promoting the overall health of the gastrointestinal system rather than reducing the secretion of stomach acid that triggers ulcers. Additional compounds with therapeutic effects include sterols and gums. Glycyrrizin has a similar structure to adrenal steroids and has been used successfully in treating adrenal insufficiency, fatigue, various skin problems, as well as female hormonal regulation. Licorice root and licorice root extracts are used in many types of supplemental formulas such as: female hormonal products, energy products, lung/demulcent products, and adrenal support products. It may also be found as a flavoring or sweetener in a variety of powders and tablets. Directions Because glycyrrhizin can cause high blood pressure and other problems, it should only be taken on the advice of a health care practitioner. Warning: Do not use licorice on a daily basis for more than five days at a time, as it can elevate blood pressure. Do not use licorice at all if you have high blood pressure. Counter-Indicators People with kidney or heart problems or a history of high blood pressure should avoid regular use of glycyrrhizin-containing licorice products. |
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